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    Introduction to Biomedical Engineering

    Systems physiology I



    Elective (Fundamental)

    Introduction to Life Science

    Physical biology

    Clinical Neuroscience

    Neural Signal Processing

    Ultrasound in Medicine

    Bioelectrial Signal Processing

    Biostatistics

    Intro. to Electrical and Mechanical Engineering for Medical Applications

    Fundamentals of Microdevices in Medicine

    Essential mathematics for DMSE

    Electromagnetic Energy in Medical Applications

    Medical Imaging System

    Hospital Onsite Education Lab.

    Neuroscience

    Clinical Neuroengineering

    Biomechanics

    Introduction to Biomedical Optics

    Biomedical Signal Analysis

    Bioelectricity

    Laser-Tissue Interactions

    Hemodynamics

    Research Project Development I

    Cellular and Molecular Medicine

    Tissue Engineering

    Biomedical optical imaging

    Precision medical device design

    Medical Robotics

    Microfluidics for biomedical applications

    Systems physiology II

    Rehabilitation Engineering

    Medical Diagonostics

    Research Project Development II

    Medical informatics

    Medical image processing

    Biomedical Materials

    Neuro-device Engineering



    Elective (Advanced / Application)

    Simulation for Nanotechnology

    Biomedical Polymers

    Bioconjugate Chemistry I

    Introduction to Life Science

    Precision medical device design

    Essential mathematics for GMSE

    Electromagnetics

    Chemistry of Nano Materials

    Supramolecular Materials

    Fundamentals of Fluid Mechanics

    Finite Element Analysis and simulations

    Medicinal Chemistry

    Bioconjugate Chemistry II

    Neuroscience I

    Introduction to the medical science

    Biomedical optics

    Medicinal Chemistry I

    Clinical Neuroengineering

    Research Project Development I

    Neuro-device Engineering

    Research Project Development II

    Interfacial Dynamics for Biomedical Applications

    Introduction to Life Science for Medical System Applications



    Research

    Research for Master Thesis

    DMSE Seminar

    Research for Ph.D. Dissertation


  • Introduction to Biomedical Engineering

    The aim of this course is to provide an introduction to biomedical engineering for students who have various backgrounds. Course material will cover a wide range of biomedical engineering areas. Throughout semester, basics of biology and medicine to engineering principles applied to biomedical applications will be intensively covered. Due to diverse subjects that have to be discussed with, several instructors will contribute on lectures in serial fashion depending on topics.



    Basic Biomedical Instrumentation Lab

    Efficient data acquisition and analysis are crucial steps of successful researches in science or engineering fields. This course is designed to provide technical information about how to acquire and analyze data during and after experiments. Throughout semester, LabVIEW will be used as a tool of data acquisition and analysis. In this lecture, students are expected to learn computer interface techniques(GPIB,RS232), analog data acquisition and analysis, image acquisition and processing techniques as well as LabVIEW programming. In addition, students are subject to carry out “independent project”, which is closely relate with his or her actual research project conducted in their lab.



    Fundamentals of Blood Flow

    In most clinical applications, it is crucial to understand blood as not only clinical subject but also engineering subject. Especially, to understand the behavior of blood flow within the body in both clinical and engineering point of views is a starting point for clinical diagnostics and therapeutics in many clinical problems. In this lecture, fundamentals of engineering mathematics will be covered as a basis of blood flow dynamics in first few weeks. Then, fundamental hemodynamics, which is the study of the deformation and flow of blood under the influence of an applied stress, is discussed as main topics throughout the semester. As following subjects, characteristic properties of macro/micro circulations will be also discussed. In addition, this lecture includes term project. Potential term project topics related with blood flow discussed in the lecture may include cardiovascular prosthetics, clinical devices, surgical applications and so on.



    Biocompatibility

    This course covers the basic biochemistry and the physiological reactions between implanted materials and physiological environments such as proteins, bloods, cells, or tissues. The materials/ body interactions including blood coagulation, inflammation, immune reaction, or wound healing will also be discussed.



    MEMS/NEMS Process and Applications

    MEMS/NEMS devices are expected to be one of the key technologies for man-machine interface and ubiquitous sensor network in the 21st-century of information society. This course will deal with MEMS/NEMS (Micro/Nano Electro Mechanical Systems) material, micro/nano fabrication process, operational principles and applications as shown below.

    Introduction to MEMS/NEMS devices and materials, semiconductor fundamentals

    Fabrication of 3D micro/nano structures, low-stress film, dry release, process integration

    Scaling effects, micro/nano electro-mechanics, optical MEMS and microfluidics

    Application examples of MEMS/NEMS devices for information and biomedical fields



    Basic Medical Science

    As a course for the one whose major is not life science, the contents of lecture are organized with essential and fundamental parts of subject in the field of biochemistry, physiology, pathology and pharmacology.



    Biomechanics

    Biomechanics is a mechanics to biology and physiology. This class provides fundamental musculoskeletal anatomy, mechanical interpretation of musculoskeletal issues, and cell mechanics. This class is designed for graduate students who want to expand their current knowledge to biomedical science, mechanobiology, rehabilitation, and sports engineering.



    Simulation for Nanotechnology

    The goal of this course is to learn practices and the theory behind and instrument called optical tweezers for manipulating nanoscale objects and measuring the interplaying forces. Firstly, microscopy is covered as it is the foundation for building this instrument. Secondly, manipulating microscopic objects and measuring picoNewton forces are discussed. Lastly, numerical simulations of laser scattering for computing the trapping forces are covered.



    Biomedical Polymers

    Lecture and discussion on biological background and the design strategy for polymeric materials for blood compatibility, tissue compatibility, drug delivery, and artificial organs. Application of polymers to various areas including cardiovascular, ophthalmic, orthopedical, dental or plastic surgical applications will be discussed.



    Introduction to Life Science

    The first segment will focus on biochemistry, tools for studying cells, and membrane function. The second segment will focus on molecular biology and genomics. The third segment will cover the cytoskeleton, cell motility and signal transduction. The final segment will cover cell adhesion, cell division and related topics. Attendance is required and periodic pop quizzes will be given at the start of class. These quizzes will cover material from the previous lectures. To prepare, review lecture notes and reading from previous lecture.



    Bioconjugate Chemistry

    Bioconjugate chemistry will be divided into independent courses: I and II during spring and fall semester, respectively. The course I is intended for students who want to acquire essential knowledge of organic chemistry and reaction. There is no prerequisite for this course because it covers general organic chemistry with the undergraduate level learned in department of chemistry. On the other hand, the course II will cover the principles and actual examples of bioconjuagtion that has been used in a variety of biological study to date.



    Precision medical device design

    This course offers mechanical/electrical engineering principles and skills which are needed at some stage during the conception, design, development, and manufacture of medical devices. Students will explore medical field as well as learn how to incorporate appropriate new technologies and refine their design using leading-edge modeling, simulation, and experimental methods.



    Essential mathematics for GMSE

    This course provides an introduction to probability and statistics with applications as well as ordinary differential equation, and partial differential equation. Students will learn how to solve mathematical problems whose solution is fundamental to many contemporary science and engineering by both analytical and practical manner



    Electromagnetics

    Electrostatics in dielectric media, Currents and magnetic fields, Origin of electricity and magnetism, Maxwell's equations, Propagation of electromagnetic wave, Radiation of electromagnetic wave



    Chemistry of Nano Materials

    The course covers the introduction to nanomaterials and is designed for students who require a knowledge of nanomaterials on an interdisciplinary basis, especially in the context with the different classes of nanomaterials, their syntheses, properties, and applications. It comprises both the theoretical and practical aspects of modern nanomaterials in view of their advanced technology. Emphasis is laid on interactive teaching, problem solving, associative and fundamental approaches. In addition, novel and advanced techniques are highlighted and discussed. All important aspects on the novel class of nanomaterials as well as their chemical, physico-chemical, and mechanical properties are included.



    Supramolecular Materials

    This course will cover the major aspects of supramolecular materials in the context of material science and chemistry for advanced students with interdisciplinary interests. It embraces the basics of these materials in terms of their different classes, properties, and applications. Interactive learning as well as fundamental study and thinking approaches are an important goal of the course



    Fundamentals of Fluid Mechanics

    Microfluidics is the study of flow phenomena at small length scales with characteristic channel dimensions typically less than the diameter of a human hair. Small length scale effects become important as surface forces such as viscous drag and surface tension govern flow behavior rather than body forces (inertia) as seen in macroscale fluid mechanics. Miniaturization of fluid handling systems also allows the development of micro Total Analysis Systems (μTAS) or so called "lab on a chip" which combines biological sample preparation, separation and analysis in a single device. Topics explored in this class include: fundamental understanding and derivation of constitutive balances in fluid mechanics, applications of the Navier-Stokes equation, and vorticity dynamics. As a final stage of this class, representative characteristics of biofluid (blood flow) will be discussed.



    Finite Element Analysis and simulations

    The finite element method to solve differential equations for engineering problems is introduced. Theoretical basis and concepts of FEM are covered with 1-D and 2-D problems. Practical approaches to FE analysis of structural, thermal, mechanical as well as multiphysics problems are covered. Element types, boundary conditions, mesh generation, and modeling considerations are discussed by using commercial finite element software.



    Medicinal Chemistry

    Current and historical drug target proteins such as receptors and the mechanism of action including structure activity relationships of small molecule ligands or drugs will be reviewed.



    Bioconjugate Chemistry II

    Bioconjugate chemistry is about themethods of how to conjugate bioactive ligands or nanomaterials to biomolecules such as proteins and DNAs. This course will cover the principles and actual examples of bioconjugation that has been used in current nano-biotechnology as well as for biological study to date. There is no pre-requisite for this class.



    Neuroscience I

    Learning objectives of this subject is to provide basic knowledge about the neuroscience for engineers. It is essential to understand the neuroanatomy, neurophysiology, and structure of neurons, which are closely related with neurological functions including motor, sensory, and cognitive functions. Basic concept of neuroscience for engineering design will be introduced for developing the therapeutic and rehabilitation devices for improving the neurological condition.



    Introduction to the medical science

    By introducing basic medical knowledge important for the engineers, this course lead students to utilize the contents for their engineering applications. The topics include the introduction to human anatomy & physiology, body fluid, membrane transport, electrophysiology, synapse & neuromuscular junction, topics about the cardiovascular and respiratory system as well as the subjects on the orthpedic and rehabilitation medicine.



    Biomedical optics

    This course introduces the theory, design of optical microscopy, and overview of key image processing techniques and its applications in biology and medicine. The course starts from an overview of basic optical principles allowing an understanding of microscopic image formation and common contrast modalities such as dark field, phase, and DIC to more advanced microscopy imaging techniques such as total internal reflection, confocal, and multiphoton. Quantitative analysis of biochemical microenvironment using spectroscopic techniques based on fluorescence, second harmonic, Raman signals will be covered.



    Medicinal Chemistry I

    Current and historical drug target proteins such as receptors and the mechanism of action including structure activity relationships of small molecule ligands or drugs will be reviewed.



    Clinical Neuroengineering

    The course is designed to provide the clinical background of neurological disorders and applied neuro-engineering field. Clinical situations which requires engineering solution will be emphasized in the course.



    Research Project Development I

    This course provides students with the opportunity to propose and develop research ideas for applications of medical diagnosis and treatment. To develop research ideas, survey of previous research results and patents, design, simulation, and preliminary experiments will be conducted. Lectures on patent analysis, research management, proposal writing, and regulations for medical devices will be offered.



    Neuro-device Engineering

    This course covers the basic anatomy and physiology of the nervous system, principles and technologies used for various neural prosthetic devices to restore hearing, vision, motor function, respiration, as well as deep brain stimulators and brain-computer interfaces. A term project on "recent advances in neuroprosthetics is included.



    Research Project Development II

    Following the RPD I, students conduct research as proposed in the research proposal developed during the RPD I. Students manage the whole process of conducting research, such as designing experiments, time scheduling, and fund management.



    Interfacial Dynamics for Biomedical Applications

    Fundamental principles governing interfacial motions will be presented along with examples found in nature and engineering systems. Topics include the motion of drop, bubble, meniscus, interfacial instability, capillary origami, fluid-structure interactions, and biolocomotion. Upon completing this course, students will be able to:

    Understand the hydrodynamic and surface forces on interfaces

    Apply the interfacial dynamics in various systems

    Analyze interfacial problems occurring in different engineering systems



    Introduction to Life Science for Medical System Applications

    This course is offered to the students whose undergraduate major is not in mechanical and/or electrical engineering. Lectures offered are on fundamentals of electric and electronic engineering including AC and DC circuit analysis, electronic circuits, logic circuits, and fundamental engineering principles in solid mechanics, kinematics, dynamics, and heat transfer for their potential applications in medical system design.



    Seminar

    Series of seminars will be offered by outstanding researchers in the filed of medical engineering areas on new and developing research topics.



    Hospital Onsite Education Lab

    This GMSE course foster medical system education opportunities for GMSE student through a Hospital Visit. The primary purpose is to introduce GMSE student medical practices, and related usage of medical devices at participating departments in hospital or clinical setting, so that student will have better understanding of medical system and further they will develop interests in this field leading to possibly improvements in medical systems in general.



    Research for Master Thesis

    Opportunity for advanced MS students to study independently in consultation with their academic advisor.



    Research for Ph.D. Dissertation

    Opportunity for advanced PhD students to study independently in consultation with their academic advisor.