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Osteoarthritis Research Laboratory

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c-Jun/activator protein-1 mediates interleukin-1beta-induced dedifferentiation but not cyclooxygenase-2 expression in articular chondrocytes.
  • AuthorHwang SG, Yu SS, Poo H, Chun JS.
  • Year2005
  • SourceJ Biol Chem. 2005 Aug 19;280(33):29780-7. Epub 2005 Jun 16. Related Articles, Links

Regulation of beta-catenin signaling and maintenance of chondrocyte differentiation by ubiquitin-independent proteasomal degradation of alpha-catenin
  • AuthorHwang SG, Yu SS, Ryu JH, Jeon HB, Yoo YJ, Eom SH, Chun JS.
  • Year2005
  • SourceJ Biol Chem. 2005 Apr 1;280(13):12758-65. Epub 2005 Jan 28. Related Articles, Links

p38 kinase mediates nitric oxide-induced apoptosis of chondrocytes through the inhibition of protein kinase C zeta by blocking autophosphorylation.
  • AuthorKim JS, Park ZY, Yoo YJ, Yu SS, Chun JS.
  • Year2005
  • SourceCell Death Differ. 2005 Mar;12(3):201-12. Related Articles, Links

Expression, activity, and regulation of MAP kinases in cultured chondrocytes.
  • AuthorChun JS.
  • Year2004
  • SourceMethods Mol Med. 2004;100:291-306. Related Articles, Links

Wnt-7a causes loss of differentiated phenotype and inhibits apoptosis of articular chondrocytes via different mechanisms.
  • AuthorHwang SG, Ryu JH, Kim IC, Jho EH, Jung HC, Kim K, Kim SJ, Chun JS.
  • Year2004
  • SourceJ Biol Chem. 2004 Jun 18;279(25):26597-604. Epub 2004 Apr 13. Related Articles, Links

Actin cytoskeletal architecture regulates nitric oxide-induced apoptosis, dedifferentiation, and cyclooxygenase-2 expression in articular chondrocytes via mitogen-activated protein kinase and protein kinase C pathways.
  • AuthorKim SJ, Hwang SG, Kim IC, Chun JS.
  • Year2003
  • SourceJ Biol Chem. 2003 Oct 24;278(43):42448-56. Epub 2003 Aug 7. Related Articles, Links

Signaling mechanisms leading to the regulation of differentiation and apoptosis of articular chondrocytes by insulin-like growth factor-1.
  • AuthorOh CD, Chun JS.
  • Year2003
  • SourceJ Biol Chem. 2003 Sep 19;278(38):36563-71. Epub 2003 Jul 9. Related Articles, Links

Retinoic acid inhibits chondrogenesis of mesenchymal cells by sustaining expression of N-cadherin and its associated proteins.
  • AuthorCho SH, Oh CD, Kim SJ, Kim IC, Chun JS.
  • Year2003
  • SourceJ Cell Biochem. 2003 Jul 1;89(4):837-47. Related Articles, Links

Protein kinase C alpha and zeta regulate nitric oxide-induced NF-kappa B activation that mediates cyclooxygenase-2 expression and apoptosis but not dedifferentiation in articular chondrocytes.
  • AuthorKim SJ, Chun JS.
  • Year2003
  • SourceBiochem Biophys Res Commun. 2003 Mar 28;303(1):206-11. Related Articles, Links

p38 kinase and c-Jun N-terminal kinase oppositely regulates tumor necrosis factor alpha-induced vascular cell adhesion molecule-1 expression and cell adhesion in chondrosarcoma cells.
  • AuthorJu JW, Kim SJ, Jun CD, Chun JS.
  • Year2002
  • SourceIUBMB Life. 2002 Nov;54(5):293-9. Related Articles, Links
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