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Cell & Virus Logistics Research Laboratory

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A lipid-anchored SNARE supports membrane fusion
  • AuthorHao Xu, Michael Zick, William T. Wickner, and Youngsoo Jun
  • Year2011
  • SourceProc. Natl. Acad. Sci. USA, 108:17325-17330

HOPS prevents the disassembly of trans-SNARE complexes by Sec17p/Sec18p during membrane fusion
  • AuthorHao Xu, Youngsoo Jun, Thompson J, Yates J, and William Wickner
  • Year2010
  • SourceThe EMBO Journal, 29:1948-1960

Human Cytomegalovirus UL18 Utilizes US6 for Evading the NK and T-Cell Responses
  • AuthorYoungkyun Kim, Boyoun Park, Sunglim Cho, Jinwook Shin, Kwangmin Cho, Youngsoo Jun, Kwangseog Ahn
  • Year2008
  • SourcePLoS Pathogens, 4:e1000123

Reconstituted membrane fusion requires regulatory lipids, SNAREs, and synergistic SNARE chaperones
  • AuthorJoji Mima, Christopher M. Hickey, Hao Xu, Youngsoo Jun, and William Wickner
  • Year2008
  • SourceThe EMBO Journal, 27:2031-2042

New Assays of Vacuole Fusion Resolve the Stages of Docking, Lipid Mixing, and Content Mixing
  • AuthorYoungsoo Jun and William Wickner
  • Year2007
  • SourceProc. Natl. Acad. Sci. USA, 104:13010-13015. (Direct Submission)

Excess Vacuolar SNAREs Drive Lysis and Rab-bypass Fusion
  • AuthorVincent Starai*, Youngsoo Jun*, and William Wickner
  • Year2007
  • SourceProc. Natl. Acad. Sci. USA, 104:13551-13558. *Co-first authors. (Feature Article, Direct Submission) - Rated “Exceptional” by the Faculty of 1000

The addition of Sec18p (NSF) and the soluble SNARE Vam7p allows a lipid-anchored R-SNARE to support yeast vacuole fusion
  • AuthorYoungsoo Jun, Hao Xu, and William Wickner
  • Year2007
  • SourceThe EMBO Journal, 26:4935-4945.

Reversible, Cooperative Reactions of Yeast Vacuole Docking
  • AuthorYoungsoo Jun, Naomi Thorngren, Vincent Starai, Rutilio A. Fratti, Kevin Collins, and William Wickner
  • Year2006
  • SourceCooperative Reactions of Yeast Vacuole Docking. The EMBO Journal, 25:5260-5269

Interdependent Assembly of Specific Regulatory Lipids and Membrane Fusion Proteins into the Vertex Ring Domain of Docked Vacuoles
  • AuthorRutilio A. Fratti, Youngsoo Jun, Alexy J. Merz, Nathan Margolis, and William Wickner
  • Year2004
  • SourceJournal of Cell Biology, 167:1087-1098

Diacylglycerol and its Formation by Phospholipase C Regulate Rab- and SNARE-dependent Yeast Vacuole Fusion
  • AuthorYoungsoo Jun, Rutilio A. Fratti, and William Wickner
  • Year2004
  • SourceThe Journal of Biological Chemistry, 279:5318653195
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