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Laboratory of Drug Discovery

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Total 189 , Page 11 / 19

Synthesis of potent chemical inhibitors of dynamin GTPase
  • AuthorSuho Lee, Kwan-Young Jung, Joohyun Park, Joong-Heui Cho, Yong-Chul Kim, Sunghoe Chang
  • Year2010
  • SourceBioorganic & medicinal chemistry letters

Design and synthesis of 1, 4-dihydropyridine derivatives as BACE-1 inhibitors
  • AuthorSoo-Jeong Choi, Joong-Heui Cho, Isak Im, So-Deok Lee, Ji-Yeon Jang, Yu-Min Oh, Yong-Keun Jung, Eun-Seok Jeon, Yong-Chul Kim
  • Year2010
  • SourceEuropean journal of medicinal chemistry

MIPs are ancestral ligands for the sex peptide receptor
  • AuthorYoung-Joon Kim, Katarina Bartalska, Neil Audsley, Naoki Yamanaka, Nilay Yapici, Ju-Youn Lee, Yong-Chul Kim, Milica Markovic, Elwyn Isaac, Yoshiaki Tanaka, Barry J Dickson
  • Year2010
  • SourceProceedings of the National Academy of Sciences

5, 5′-substituted indirubin-3′-oxime derivatives as potent cyclin-dependent kinase inhibitors with anticancer activity
  • AuthorSoo-Jeong Choi, Jung-Eun Lee, Soon-Young Jeong, Isak Im, So-Deok Lee, Eun-Jin Lee, Sang Kook Lee, Seong-Min Kwon, Sang-Gun Ahn, Jung-Hoon Yoon, Sun-Young Han, Jae-Il Kim, Yong-Chul Kim
  • Year2010
  • SourceJournal of medicinal chemistry

Indirubin derivatives as potent FLT3 inhibitors with anti-proliferative activity of acute myeloid leukemic cells
  • AuthorSoo Jeong Choi, Myoung Ju Moon, So Deok Lee, Sang-Un Choi, Sun-Young Han, Yong-Chul Kim
  • Year2010
  • SourceBioorganic & medicinal chemistry letters

5′-Nitro-indirubinoxime induces G1 cell cycle arrest and apoptosis in salivary gland adenocarcinoma cells through the inhibition of Notch-1 signaling
  • AuthorJi-Hye Yoon, Soo-A Kim, Seong-Min Kwon, Jong-Hwan Park, Hee-Sae Park, Yong-Chul Kim, Jung-Hoon Yoon, Sang-Gun Ahn
  • Year2010
  • SourceBiochimica et Biophysica Acta (BBA)-General Subjects

Diverse Effects of a Benzofuroindole on Different K+ Channels and Localization of Its Receptor on BKCa Channel
  • AuthorByoung-Cheol Lee, Hyun-Ho Lim, Hyun-Ju Kim, Yong-Chul Kim, Chul-Seung Park
  • Year2010
  • SourceBiophysical Journal

Total synthesis of 8-oxypseudopalmatine and 8-oxypseudoberberine via ring-closing metathesis
  • AuthorHue Thi My Van, Su Hui Yang, Daulat Bikram Khadka, Yong-Chul Kim, Won-Jea Cho
  • Year2009
  • SourceTetrahedron

Efficient preparation of highly pure chlorin e6 and its photodynamic anti-cancer activity in a rat tumor model
  • AuthorYeon-Hee Moon, Seong-Min Kwon, Hyo-Jun Kim, Kwan-Young Jung, Jong-Hwan Park, Soo-A Kim, Yong-Chul Kim, Sang-Gun Ahn, Jung-Hoon Yoon
  • Year2009
  • SourceOncology reports

Synthesis and structure–activity relationships of pyrazolodiazepine derivatives as human P2X7 receptor antagonists
  • AuthorJu-Yeon Lee, Juan Yu, Won Je Cho, Hyojin Ko, Yong-Chul Kim
  • Year2009
  • SourceBioorganic & medicinal chemistry letters
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