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Osteoarthritis Research Laboratory

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Estrogen-related receptor γ causes osteoarthritis by upregulating extracellular matrix-degrading enzymes
  • Year2017
  • SourceNat Commun. 2017 Dec

Upregulation of lipocalin-2 (LCN2) in osteoarthritic cartilage is not necessary for cartilage destruction in mice
  • Year2016
  • SourceOsteoarthritis Cartilage. 2016 Jul

Upregulation of Atrogin-1/FBXO32 is not necessary for cartilage destruction in mouse models of osteoarthritis
  • Year2016
  • SourceOsteoarthritis Cartilage. 2016 Jul.

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction
  • Year2016
  • SourceAnn Rheum Dis. 2016 May

Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis
  • Year2016
  • SourceAnn Rheum Dis. 2016 Feb

HIF-2α-induced chemokines stimulate motility of fibroblast-like synoviocytes and chondrocytes into the cartilage-pannus interface in experimental rheumatoid arthritis mouse models
  • Year2015
  • SourceArthritis Res Ther. 17:302

Reciprocal activation of hypoxia-inducible factor (HIF)-2α and the zinc-ZIP8-MTF1 axis amplifies catabolic signaling in osteoarthritis
  • Year2015
  • SourceOsteoarthritis and Cartilage.2015.Aug.

Reciprocal regulation by hypoxia-inducible factor-2α and the NAMPT-NAD+-SIRT axis in articular chondrocytes is involved in osteoarthritis
  • Year2015
  • SourceOsteoarthritis and Cartilage. 2015. Jul.

Matrix crosslinking-mediated mechanotransduction promotes post-traumatic osteoarthritis
  • Year2015
  • SourcePNAS.2015.jun.

Macrophage HIF-2α ameliorates adipose tissue inflammation and insulin resistance in obesity
  • Year2014
  • SourceDiabetes. 2014 Oct;63(10):3359-71.
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