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RNA Genomics and Epigenetics Laboratory

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Widespread Alternative Splicing Changes in Metastatic Breast Cancer Cells.
  • AuthorOh J, Pradella D, Shao C, Li H, Choi N, Ha J, Ruggiero S, Fu XD, Zheng X, Ghigna C, Shen H.
  • Year2021
  • SourceCells. 2021 Apr 9;10(4):858.

SRSF9 Regulates Cassette Exon Splicing of Caspase-2 by Interacting with Its Downstream Exon
  • AuthorHa J, Jang H, Choi N, Oh J, Min C, Pradella D, Jung D-W, Williams DR, Park D, Ghigna C, Zheng X, Shen H.
  • Year2021
  • SourceCells 2021, 10(3), 679.

U2AF65-Dependent SF3B1 Function in SMN Alternative Splicing.
  • AuthorChoi N, Liu Y, Oh J, Ha J, Zheng X, Shen H.
  • Year2020
  • SourceCells. 2020 Dec 9;9(12):2647.

Opposite Roles of Tra2β and SRSF9 in the v10 Exon Splicing of CD44.
  • AuthorOh J, Liu Y, Choi N, Ha J, Pradella D, Ghigna C, Zheng X, Shen H.
  • Year2020
  • SourceCancers (Basel). 2020 Oct 30;12(11):3195.

Relative strength of 5' splice-site strength defines functions of SRSF2 and SRSF6 in alternative splicing of Bcl-x pre-mRNA
  • AuthorChoi N, Liu Y, Oh J, Ha J, Ghigna C, Zheng X, Shen H.
  • Year2020
  • SourceBMB Rep. 2020 Oct 14:5137.

hnRNP A1 Regulates Alternative Splicing of Tau Exon 10 by Targeting 3' Splice Sites
  • AuthorLiu Y, Kim D, Choi N, Oh J, Ha J, Zhou J, Zheng X, Shen H.
  • Year2020
  • SourceCells. 2020 Apr 10;9(4):936.

RRM but not the Asp/Glu domain of hnRNP C1/C2 is required for splicing regulation of Ron exon 11 pre-mRNA
  • AuthorMoon H, Jang HN, Liu Y, Choi N, Oh J, Ha J, Kim HH, Zheng X, Shen H.
  • Year2019
  • SourceBMB Reports 2019; 52(11): 641-646

Activation of Cryptic 3' Splice-Sites by SRSF2 Contributes to Cassette Exon Skipping
  • AuthorMoon H, Jang HN, Liu Y, Choi N, Oh J, Ha J, Zheng X, Shen H.
  • Year2019
  • SourceCells. 2019 Jul 10;8(7):696.

Binding of SRSF4 to a novel enhancer modulates splicing of exon 6 of Fas pre-mRNA.
  • AuthorJang, H., Liu, Y., Choi, N., Oh, J., Ha, J., Zheng, X., Shen, H.
  • Year2018
  • SourceBiochemical and Biophysical Research Communications, 506(3), p.703-708

SRSF2 directly inhibits intron splicing to suppresses cassette exon inclusion.
  • AuthorMoon, H., Cho, S., Loh, T., Jang, H., Liu, Y., Choi, N., Oh, J., Ha, J., Zhou, J., Cho, S., Kim, D., Ye, M., Zheng, X., Shen, H.
  • Year2017
  • SourceBMB Reports, 50(8), p.423-428
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