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Membrane protein Structural and functional biology Laboratory

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Discovery of Triazolopyrimidine Derivatives as Selective P2X3 Receptor Antagonists Binding to an Unprecedented Allosteric Site as Evidenced by Cryo-Electron Microscopy
  • AuthorGa-Ram Kim, Subin Kim, Yeo-Ok Kim, Xuehao Han, Jessica Nagel, Jihyun Kim, Dahin Irene Song, Christa E. Müller, Myung-Ha Yoon, Mi Sun Jin, and Yong-Chul Kim
  • Year2024
  • SourceJournal of Medicinal Chemistry 2024 67 (16), 14443-14465 DOI: 10.1021/acs.jmedchem.4c01214

Activation mechanism and novel binding sites of the BKCa channel activator CTIBD
  • AuthorNarasaem Lee, Subin Kim, Na Young Lee, Heeji Jo, Pyeonghwa Jeong, Haushabhau S Pagire, Suvarna H Pagire, Jin Hee Ahn, Mi Sun Jin, Chul-Seung Park
  • Year2024
  • SourceLife Science Alliance Aug 2024, 7 (10) e202402621; DOI: 10.26508/lsa.202402621

Cryo-EM structure of the human glucose transporter GLUT7
  • AuthorSang Soo Lee, Subin Kim, Mi Sun Jin
  • Year2024
  • SourceBiochemical and Biophysical Research Communications volume 798, Article number: 150544 (2024)

Cryo-EM structure of cadmium-bound human ABCB6
  • AuthorSeung Hun Choi, Sang Soo Lee, Hyeon You Lee, Subin Kim, Ji Won Kim & Mi Sun Jin
  • Year2024
  • SourceCommunications Biology volume 7, Article number: 672 (2024)

W546 stacking disruption traps the human porphyrin transporter ABCB6 in an outward-facing transient state
  • AuthorSang Soo Lee, Jun Gyou Park, Eunhong Jang, Seung Hun Choi, Subin Kim, Ji Won Kim & Mi Sun Jin
  • Year2023
  • SourceCommunications Biology volume 6, Article number: 960 (2023)

The lysosomal transporter TAPL has a dual role as peptide translocator and phosphatidylserine floppase
  • AuthorJun Gyou Park, Songwon Kim, Eunhong Jang, Seung Hun Choi, Hyunsu Han, Seulgi Ju, Ji Won Kim, Da Sol Min & Mi Sun Jin
  • Year2022
  • SourceNature Communications volume 13, Article number: 5851 (2022)

Structural insights into novel mechanisms of inhibition of the major β-carbonic anhydrase CafB from the pathogenic fungus Aspergillus fumigatus
  • AuthorKim S, Yeon J, Sung J, Kim NJ, Hong S, Jin MS
  • Year2021
  • SourceJ Struct Biol. 2021 Mar;213(1):107700.

Crystal Structure of β-Carbonic Anhydrase CafA from the Fungal Pathogen Aspergillus fumigatus
  • AuthorKim S, Yeon J, Sung J, Jin MS
  • Year2020
  • SourceMol Cells. 2020 Sep 30;43(9):831-840.

The structural basis of the low catalytic activities of the two minor β-carbonic anhydrases of the filamentous fungus Aspergillus fumigatus
  • AuthorKim S, Kim NJ, Hong S, Kim S, Sung J, Jin MS
  • Year2019
  • SourceJ Struct Biol. 2019;208(1):61-68.

Application of antihelix antibodies in protein structure determination
  • AuthorJi Won Kim, Songwon Kim, Haerim Lee, Geunyoung Cho, Sun Chang Kim, Hayyoung Lee, Mi Sun Jin, Jie-Oh Lee
  • Year2019
  • SourceProc Natl Acad Sci U S A. 2019;116(36):17786-17791
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