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Laboratory of Drug Discovery

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Total 189 , Page 2 / 19

Discovery of 5-methyl-1H-benzo [d] imidazole derivatives as novel P2X3 Receptor Antagonists
  • AuthorJinsu Bae, Koon Mook Kang, Yong-Chul Kim
  • Year2022
  • SourceBioorganic & Medicinal Chemistry Letters

Discovery of substituted indole derivatives as allosteric inhibitors of m6A‐RNA methyltransferase, METTL3‐14 complex
  • AuthorJe-Heon Lee, Subin Kim, Mi Sun Jin, Yong‐Chul Kim
  • Year2022
  • SourceDrug Development Research

Eltrombopag as an Allosteric Inhibitor of the METTL3-14 Complex Affecting the m6A Methylation of RNA in Acute Myeloid Leukemia Cells
  • AuthorJe-Heon Lee, Namjeong Choi, Subin Kim, Mi Sun Jin, Haihong Shen, Yong-Chul Kim
  • Year2022
  • SourcePharmaceuticals

Development of Dibenzothiazepine Derivatives as Multifunctional Compounds for Neuropathic Pain
  • AuthorYoung-Hwan Jung, Yeo Ok Kim, Koon Mook Kang, Hyung Gon Lee, Borum Son, Xuehao Han, Eunseok Oh, Siwon Kim, Seon Hee Seo, Jong-Hyun Park, Ki Duk Park, Woong Mo Kim, Myung Ha Yoon, Yong-Chul Kim
  • Year2022
  • SourcePharmaceuticals

Involvement of endoplasmic reticulum stress and cell death by synthesized Pa-PDT in oral squamous cell carcinoma cells
  • AuthorHyo-Eun Yoon, Mee-Young Ahn, Yong-Chul Kim, Jung-Hoon Yoon
  • Year2022
  • SourceJournal of Dental Sciences

Synthesis and Structure–Activity Relationship Studies of Benzimidazole-4, 7-dione-Based P2X3 Receptor Antagonists as Novel Anti-Nociceptive Agents
  • AuthorJinsu Bae, Yeo-Ok Kim, Xuehao Han, Myung-Ha Yoon, Woong-Mo Kim, Yong-Chul Kim
  • Year2022
  • SourceMolecules

Synthesis and structure-activity relationship studies of 1, 5-isomers of triazole-pyrrolopyrimidine as selective Janus kinase 1 (JAK1) inhibitors
  • AuthorWooChan Kim, Sun-Mi Lee, Pyeong-Hwa Jeong, Jae-Hoon Jung, Yong-Chul Kim
  • Year2022
  • SourceBioorganic & Medicinal Chemistry Letters

Discovery of Novel Pyrimidine-Based Capsid Assembly Modulators as Potent Anti-HBV Agents
  • AuthorWooChan Kim, Jung-Ah Kang, Minji Park, Pyeong-Hwa Jeong, Yoon Jun Kim, Yuri Cho, Sung-Gyoo Park, Yong-Chul Kim
  • Year2021/4/23
  • SourceJournal of Medicinal Chemistry

Characterization of LDD-2633 as a Novel RET Kinase Inhibitor with Anti-Tumor Effects in Thyroid Cancer
  • AuthorHyo Jeong Lee, Pyeonghwa Jeong, Yeongyu Moon, Jungil Choi, Jeong Doo Heo, Yong-Chul Kim, Sun-Young Han
  • Year2021/1
  • SourcePharmaceuticals

Discovery of orally active indirubin-3′-oxime derivatives as potent type 1 FLT3 inhibitors for acute myeloid leukemia
  • AuthorPyeonghwa Jeong, Yeongyu Moon, Je-Heon Lee, So-Deok Lee, Jiyeon Park, Jungeun Lee, Jiheon Kim, Hyo Jeong Lee, Na Yoon Kim, Jungil Choi, Jeong Doo Heo, Ji Eun Shin, Hyun Woo Park, Yoon-Gyoon Kim, Sun-Young Han, Yong-Chul Kim
  • Year2020/6/1
  • SourceEuropean journal of medicinal chemistry
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